Reviews of Physiology, Biochemistry and Pharmacology

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Beschreibung

In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR function and focusses on the underlying mechanisms of GPCR malfunctions responsible for diferent human diseases.

Inhalt
Phospholipase D -- structure, regulation and function.-Endotoxin tolerance -- mechanisms and beneficial effects in bacterial infection.-The structural basis of G-protein-coupled receptor function and dysfunction in human disease.

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Produktinformationen

Titel
Reviews of Physiology, Biochemistry and Pharmacology
Beiträge von
EAN
9783662310076
ISBN
3662310074
Format
Kartonierter Einband
Herausgeber
Springer Berlin Heidelberg
Genre
Medizin
Anzahl Seiten
236
Gewicht
365g
Größe
H235mm x B155mm x T12mm
Jahr
2014
Untertitel
Englisch
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