Haschek and Rousseaux's Handbook of Toxicologic Pathology Volume 1

(0) Donner la première évaluation
CHF 229.90
Download est disponible immédiatement
eBook (epub)
Informations sur les eBooks
Les eBooks conviennent également aux appareils mobiles (voir les instructions).
Les eBooks d'Ex Libris sont protégés contre la copie par ADOBE DRM: apprenez-en plus.
Pour plus d'informations, cliquez ici.


Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Completely revised with a number of new chapters, Volume 1 of the Handbook of Toxicologic Pathology is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

  • Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology
  • Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology
  • Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations


1. Toxicology Pathology: An Introduction

Part 1 Principles of Toxicologic Pathology 2. Biochemical and Molecular Basis of Toxicity 3. ADME Principles in Small Molecule Drug Discovery and Development: An Industrial Perspective 4. Biotherapeutic ADME and PK/PD Principles 5. Principles of Pharmacodynamics and Toxicodynamics 6. Morphologic Manifestations of Toxic Cell Injury 7. The Role of Pathology in Evaluation of Reproductive, Developmental, and Juvenile Toxicity 8. Carcinogenesis: Mechanisms and Evaluation

Part 2 Methods in Toxicologic Pathology 9. Basic Approaches to Anatomic Toxicologic Pathology 10. Clinical Pathology in Nonclinical Toxicity Testing 11. Special Techniques in Toxicologic Pathology 12. Digital Pathology and Tissue Image Analysis 13. In Vivo Small Animal Imaging: A Comparison to Gross and Histopathologic Observations in Animal Models 14. Biomarkers: Discovery, Qualification and Application 15. Toxicogenomics: A Primer for Toxicologic Pathologists 16. Experimental Design and Statistical Analysis for Toxicologic Pathologists

Part 3 Animal and Alternative Models in Toxicologic Research 17. Animal Models in Toxicologic Research: Rodents 18. Animal Models in Toxicologic Research: Rabbit 19. Animal Models in Toxicologic Research: Dog 20. Animal Models in Toxicologic Research: Pig 21. Animal Models in Toxicologic Research: Nonhuman Primate 22. Animal Models in Toxicologic Research: Non-mammalian 23. Genetically Engineered Animal Models in Toxicologic Research 24. Alternative Models in Biomedical Research: In Silico, In Vitro, Ex Vivo, and Non-Traditional In Vivo Approaches

Part 4 Practice of Toxicologic Pathology 25. Nomenclature and Diagnostic Resources in Anatomic Toxicologic Pathology 26. Pathology Peer Review 27. Pathology and GLPs, Quality Control and Quality Assurance 28. Practices to Optimize Generation, Interpretation, And Reporting of Pathology Data from Toxicity Studies 29. Issues in Laboratory Animal Science that Impact Toxicologic Pathology

Afficher plus

Détails sur le produit

Haschek and Rousseaux's Handbook of Toxicologic Pathology Volume 1
Principles and Practice of Toxicologic Pathology
eBook (epub)
Elsevier Science & Techn.
Protection contre la copie numérique
Taille de fichier
26.41 MB
Nombre de pages
Afficher plus
Les clients ayant acheté cet article ont également acheté :